Acute myeloid leukemia with NUP98 rearrangement

Rare.. and somewhat tricky to identify... but clinically relevant.

AML with nucleoporin 98 gene (NUP98) rearrangement is described as a “rare” entity.. however, I’ve been coming across these cases more and more these days.. which prompted me to share an example with you because I think recognizing this entity will become more and more important as menin-inhibitors move into the front line setting for therapy. Allow me …